| Researchers with the Lawrence Berkeley National Laboratory (Berkeley Lab) have invented a technique in which DNA or RNA assays (for genetic profiling and disease detection) can be read and evaluated without the need for elaborate expensive chemical labeling or sophisticated instrumentation.
A new method for reading DNA (or RNA) microarrays is based on measuring the electrostatic repulsion between silica microspheres and hybridized DNA. Surface areas containing double-stranded DNA (red) or single-stranded DNA (blue) can be easily distinguished from each other and from background areas by the naked eye. (Flavio Robles, Berkeley Lab Public Affairs)
Berkeley Lab news release
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